What are Dendritic Cell?
Dendritic Cells are specialized antigen processing cells. They possess a large number of receptor-attached receptors which facilitate the uptake of immunoglobulin components, and they’re specialized to convert the antigen-receptor complexes into MHC peptide complexes that are recognized by cells called T cells in the body. But how do Dendritic Cells work? How do they help the body fight infection and disease?
First, let’s have a quick overview of what a Dendritic Cell actually is. Dendritics are very large-diameter cells, often much bigger than red blood cells, which have long “dendritic spines” or branches extending from the cell’s nucleus into a cyst-like structure. Dendritics are also commonly referred to as macrophages. Macrophages are small-sized antigen-processing cells, which engulf pathogens and other foreign matter into their digestive tracts. In fact, macrophages are the body’s most potent killers; many scientists believe they’re the body’s natural defense against pathogens.
So what do Dendritic Cells do? What are their primary functions? There are a variety of theories about Dendritics’ role in the immune system. Some researchers believe they play a role in recognition of infection or disease-causing agents, while others point to the role of Dendritics in recognizing and destroying foreign substances. And still others believe they play a role in the maintenance of the innate immune response.
The role of the Dendritic Cell (DC) cells is not yet well understood, but it’s believed that they may play multiple roles within the body. For example, they may actively participate in the body’s fight against bacteria and viruses, or they may help to regulate the innate immunity. In addition, Dendritics may also directly support the innate immune response by secreting a variety of cytokines and chemokines, which are involved in the generation and maintenance of the body’s own defense mechanisms. Finally, DCs may also produce a variety of cytokines and chemokines that regulate the release and activity of T-cells.
Because they’re so large, Dendritics can also be thought of as having a role in the regulation of the innate immune response. When T-cells and B-cells are overactive, Dendritics can help to control this overactivity by reducing the number of T-cells and B-cells. This helps to maintain a balance between the body’s primary defense mechanism and the development and spread of infection. And because Dendritics are so large, they can also be thought of as playing a role in the regulation of T-cell activity. These cells can inhibit T-cells from recognizing specific antigen and can decrease the production of a wide range of cytokines, including IL-1, IL-6, and CXCL-2.
When you consider how Dendritics affect the body, it becomes clear that they may also have a role in the regulation of the immune response. For instance, if a person is infected, Dendritics can actively attack pathogens and eliminate them through their action on antigen-presenting cells, which release inflammatory cytokines and chemokines, thus reducing the amount of immune cell activation and activity. They may also actively assist T-cells by secreting a variety of cytokines that aid in the activation of T-cells and the production of chemokines and cytokines.
The role of Dendritic Cell in the regulation of the innate immune response is one of the major benefits of using the product called Dendreon’s Multi Dendritic Immune System. This system uses a proprietary mixture of proprietary Dendreon’s cytokine stimulators and anti-inflammatory agents to effectively regulate both the innate immune response and T-cell activity and to eliminate harmful pathogens. By providing comprehensive protection against various infections, Dendreon’s Multi Dendritic Cell Immune System may prove to be a beneficial treatment for conditions that have been resistant to other, more traditional methods of disease prevention and treatment.